盐酸戊乙奎醚麻醉前用药对小儿麻醉恢复期的影响

摘要

目的：观察盐酸戊乙奎醚麻醉前用药对小儿麻醉恢复期的影响。方法：选取2013年11月～2014年10月在我院进行腹腔镜隐睾手术治疗的患儿200例，按照随机分组的方式分为A组（盐酸戊乙奎醚）100例和B组（阿托品）100例。收集两组患儿用药前、用药后10min、20min、30min的平均动脉压（MAP）、心率（HR）、收缩压×心率（RPP）、体温（T）、VAS评分情况以及两组患儿麻醉苏醒时间、拔管时间、复苏室停留时间等数据，并进行统计学分析。结果：两组患儿在用药前HR、MAP、RPP、T数据比较无明显差异，无统计学意义（P>0.05）。在用药后A组与用药前比较数据差异不明显，无统计学意义（P>0.05）。而B组HR、MAP、RPP、T值均较用药前有所升高，数据比较差异明显，具有统计学意义（P<0.05）。两组患儿用药后VAS评分均较用药前降低，但是两组比较数据差异不明显，无统计学意义（P>0.05）。两组患儿的麻醉苏醒时间、拔管时间、复苏室停留时间A组明显小于B组，数据比较差异明显，具有统计学意义（P<0.05）。结论：盐酸戊乙奎醚作为小儿麻醉前用药在麻醉效果方面和阿托品相当，而在麻醉恢复阶段较为有利于患儿的苏醒，值得临床推广。%Objective: Effects of encyclopedic hydro chloride deprecation in pediatric anesthesia recovery period. Methods: November 2013 to October 2014 for one year at our hospital for children between hypothyroidism macroscopic surgery 200 cases, according to randomized divided into Group A (HCl penehyclidine) 100 cases and B group (atropine) 100 cases. Two groups of children were collected before treatment, after treatment, 10min, 20min, 30min mean arterial pressure (MAP), heart rate (HR), systolic blood pressure × heart rate (RPP), temperature (T), VAS score, as well as two groups of children anesthesia time, extrication time, recovery room residence time and other data, and statistical analysis. Results:The two groups in the before treatment HR, MAP, RPP, T data showed that the difference between, was not statistically significant (P>0.05). The difference in A after the treatment group before and after treatment to compare data is not obvious, is not statistically significant(P>0.05). While in B group, HR, MAP, RPP, T values were compared with that before treatment was increased, the data difference, with statistical significance(P<0.05). Two groups after treatment VAS score decreased, but compared to the data difference between the two groups was not obvious, is not statistically significant (P>0.05). The anesthesia recovery time, extrication time, recovery room for two groups of children with residence time in A group was significantly less than group B, data difference, with statistical significance (P<0.05).Conclusion: Encyclopedic hydro chloride as deprecation in pediatric anesthesia anesthetic effect and atropine effect quite, but in anesthesia recovery stage more conducive to children wake up, is worth the clinical promotion.