Objectives: To evaluate the prevalence and risk factors of pulmonary embolism ( PE ) in patients with malignant tumor. Methods: Data of 486 patients with malignant tumor, who received multi-detector thoracic CT during January 2008 to December 2009, were retrospectively reviewed. The incidences of PE in the patients with or without surgery, chemotherapy, or radiotherapy were analyzed. Results: PE was detected in 18 patients ( 3. 7% ). There was no significant difference in PE prevalence between female and male patients, or among different typings of tumors ( P > 0. 05 ). Meanwhile, there was no significant difference in PE prevalence between the patients with and without distant metastasis, or between patients with and without chemotherapy ( P > 0. 05 ). However , significantly higher risk of PE was revealed in patients received surgery or chemotherapy in the last 3 months than that in those did not ( P < 0. 05 ). Conclusion: Patients with malignant tumor who received surgery or chemotherapy recently should be monitored for PE.%目的:探讨恶性肿瘤患者肺动脉检塞(PE)发生率,以及肿瘤类型、远处转移、治疗方式、住院等风险因素对PE发生率的影响.方法:回顾性分析广东省中医院2008年1月-2009年12月收治的486例恶性种瘤患者的胸部CT增强扫描资料,统计患者无症状PE的检出率,对不同性别、不同肿瘤类型,接受手术、化学治疗、放射治疗患者与未接受手术、化学治疗、放射治疗的患者的PE发生率进行比较.结果:18例患者检出PE,发生率为3.7%,男、女性肿瘤患者PE发生率比较差异无统计学意义,不同类型肿瘤PE发生率比较差异无统计学意义(P＞0.05);肿瘤远处转移、接受放射治疗的恶性肿瘤患者PE发生率与无肿瘤远处转移、未接受放射治疗患者比较,差异无统计学意义,但近3个月内接受手术、化学治疗者PE发生率高于未接受手术、化学治疗者(P<0.05).结论:对近期(3个月内)内接受手术、化学治疗的恶性肿瘤患者,临床需要密切监测,防范PE发生及其不良后果的可能.
展开▼
