Objective: To explore the therapeutic effect of desmopressin and dry bed training in primary nocturnal enuresis. Method: Eighty-sever children with Primary Nocturnal Enuresis were randomly divided into two groups. Desmopressin group (51 cases) was treated by desmoprsessin with dry bed training for three months; Chinese medicine group (36 cases) was treated by Chinese medicine with dry bed training for three courses. Clinical efficacy and adverse effects were observed and compared. Result: The effective rate was 88% in the desmopressin group and 67% in the chinese medicine group with a significant difference between the two groups ( P < 0. 05). The reoccurrence rate was 36% in the desmopressin group and 50% in the chinese medicine group with a nosignifi-cant difference between the two groups (P > 0. 05). Conclusion: Desmopressin is effective and convenient and less side-effect in the treatment of PNE.%目的:分析弥凝结合干床训练治疗小儿遗尿症(PNE)的疗效.方法:将87例确诊为PNE的患儿随机分为弥凝治疗组(51例)和中药治疗组(36例),弥凝治疗组采用弥凝(0.1 mg/d,睡前顿服,连服3个月)联合干床训练治疗;中药治疗组采用中药结合干床训练治疗,连服3个疗程.观察两组临床疗效及不良反应.结果:弥凝治疗组有效率高于中药治疗组(88%对比67%),比较差异有统计学意义(P<0.05).弥凝治疗组复发率低于中药治疗组(36%对比50%),但两组比较差异无统计学意义(P>0.05).结论:弥凝结合干床治疗PNE疗效好,不良反应少.
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