老年心血管疾病合并阻塞性睡眠呼吸暂停综合征的临床治疗评价

摘要

Objective To analyze the relationship between cardiovascular disease and obstructive sleep apnea syndrome (OS-AHS) in senior patients,and also to explore treatment methods for cardiovascular disease complicated with OSAHS.Methods Sixty senior patients with cardiovascular disease complicated with OSAHS admitted into our hospital for treatment from December 2015 to December 2016 were designated as the observation group,while another 60 subjects who underwent physical examination in the hospital were selected as the control group.The patients in the observation group all received noninvasive mechanical ventilation,while the subjects in the control group were not given noninvasive mechanical ventilation.Heart rate and blood pressure of the groups were all detected by polysomnography and the results thus obtained were compared and analyzed.Results Detection results showed that the number of ventricular premature beats and the number of supraventricular extrasystoles in the patients of the observation group were significantly greater than those in the subjects of the control group (P ＜ 0.05).There was statistical significance in the differences of mean arterial pressure,mean apnea time,maximum apnea time and respiratory disturbance in the subjects of the 2 groups,when comparisons were made between them (P ＜ 0.05).Following treatment,there were 32 effective cases,accounting for 95.0％ (57/60) in the patients of the observation group.The partial pressure of carbon dioxide,PH value,arterial oxygen pressure were significantly improved as compared with those before treatment,with statistical significance (P ＜ 0.05).Conclusion Cardiovascular disease was closely associated with obstructive sleep apnea syndrome.Noninvasive mechanical ventilation could achieve effective therapeutic results in the treatment of cardiovascular disease complicated with obstructive sleep apnea syndrome,which was worth further clinical extension.%目的 分析老年心血管疾病与阻塞性睡眠呼吸暂停综合征(obstructive sleep apnea syndrome,OSAHS)之间的关系,并探讨老年心血管疾病合并OSAHS的治疗方法.方法 选取我院2015年12月至2016年12月我院收治的老年心血管疾病合并OSAHS患者60例(观察组);选取同期入我院进行体检的健康人群60例作为对照(对照组).观察组患者均接受无创机械通气治疗,对照组不采用无创机械通气治疗.2组人群均采用多导睡眠呼吸检测仪检测其心律和血压的变化,并对结果进行对比分析.结果 检测结果显示,观察组患者室性早搏次数和室上性早搏次数均明显多于对照组(P＜0.05),2组人群的平均动脉压、平均呼吸暂停时间、最长呼吸暂停时间和呼吸紊乱次数比较差异均有统计学意义(P＜0.05).经治疗后观察组显效32例,有效25例,无效3例,治疗总有效率为95.0％ (57/60);其二氧化碳分压和动脉血氧分压均较治疗前明显改善,2组比较差异均有统计学意义(P＜0.05).结论 老年心血管疾病与OSAHS关系密切,采用无创机械通气治疗老年心血管疾病与合并OSAHS疗效显著,值得临床推广.