目的 现察肺心痛急性发作期中西医结合综合治疗方案的临床疗效.方法 将122例肺心病急性发作期患者随机分为2组,治疗组采用中西医结合综合方案(西医常规化治疗基础上,辨证分型为痰湿壅肺证者给予基础方:三拗汤十瓜蒌薤白半夏汤十桔梗汤；肺脾两虚型者在基础方上加香砂六君子；阳虚水泛型在基础方上加苓桂术甘汤)治疗,对照组采用西医常规化治疗.2组均治疗14d.观察2组患者综合疗效评定、主要症状、体征、血气分析结果、基于患者报告的结局评价(PRO)的差异.结果 治疗组在综合疗效评定、主要症状、体征、血气分析结果、基于患者报告的结局评价(PRO)等方面均优于对照组,差异有统计学意义(P＜0.05).结论 肺心痛急性发作期采用中西医结合治疗方案能提高总体疗效,改善症状、体征、血气分析结果,提高生活质量.%OBJECTIVE To observe the clinical efficacy of the comprehensive therapy of the integration of traditional Chinese medicine (TCM) and Western medicine for pulmonary heart disease at acute stage. METHODS 122 patients were randomly divided into 2 groups. The comprehensive therapy which combined Western routine treatment and TCM differentiation was applied for treatment group. Patients with phlegm obstructed in the lung syndrome were given San'ao Decoction, Guaxieban Decoction and Jiegeng Decoction; lung and spleen deficiency syndrome was added Xiangsha Liujun-zi; and edema due to yang insufficiency syndrome plus Lingguizhugan Decoction. While, control group were offered only Western routine treatment. The experimental course was 14 days. Afterwards, the patients' overall efficacy assessment, the main symptoms and signs, blood gas analysis and PRO were under observation. RESULTS The outcomes of the a-bove items of treatment group were superior to control group, showing statistical significance (P<0.05). CONCLUSION The comprehensive therapy of the integration of TCM and Western medicine for pulmonary heart disease at acute stage proved to improve the overall efficacy, symptoms, signs, blood gas analysis results and patients' quality of life.
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