目的 应用洛文斯顿作业疗法认知评定量表(第2版)(LOTCA-Ⅱ)初步探讨多发性硬化(Ms)患者的认知功能障碍特点.方法 应用LOTCA-Ⅱ量表对41例MS患者(MS组)及45例正常健康者(对照组)的认知情况进行评估,对比2组LOTCA-Ⅱ量表各项评分的差异.结果 在视知觉、空间知觉、视运动组织、注意力与专注力4个子项目方面,MS组评分明显低于对照组(P＜0.05)；在几何图形识别、图形重叠识别、身体方位、与周围物体关系、图片中的空间关系、临摹几何图形、复绘二维图形、插孔拼图、彩色方块拼图、无色方块拼图、碎图复原、画钟面、图片排序A、图片排序B、逻辑问题15个次级子项目方面,MS组评分明显低于对照组(P＜0.05).结论 MS患者认知功能障碍主要表现在视知觉、空间知觉、视运动组织、注意力与专注力4个方面；LOTCA-Ⅱ量表可较为灵敏、全面地反映MS患者执行功能减退的程度,可用来早期评价MS患者的认知功能.%Objective To determine the cognitive impairment using Loewenstein Occupational Therapy Cognitive Assessment-Second Edition (LOTCA-Ⅱ)in patients with multiple sclerosis (MS).Methods The cognitive situation was assessed using LOTCA-Ⅱ in 41 MS patients (MS group) and 45 healthy subjects (control group).The scores on the LOTCA subtests were compared between the two groups.Results Compared with control group,the scores on visual perception,spatial perception,visuomotor organization,and attention and concentration significantly decreased in MS group (P＜0.05).In addition,MS patients had lower scores on geometric figure recognition,graphic overlap identification,body orientation,relationship to surrounding objects,spatial relations in picture,copying geometric figure,reproduction of two-dimensional figure,pegboard construction,colored block-design,plain block-design,reproduction of puzzle,drawing clock,pictorial sequence A,pictorial sequence B and logic questions than healthy subjects (P＜0.05).Conclusion Cognitive impairment of MS patients is mainly related to visual perception,spatial perception,visuomotor organization,and attention and concentration.LOTCA-Ⅱmay sensitively and comprehensively reflect the degree of executive dysfunction and can be used to evaluate the cognitive function in MS patients.
展开▼
