分次立体定向伽玛刀配合盆腔放疗治疗宫颈癌的临床观察

摘要

Objective:To discuss the efficacy of whole pelvic radiation therapy plus gamma knife treatment of cervical cancer. Methods: Sixty patients with advanced cervical cancer were treated with whole pelvic radiation therapy with dose 46 -50Gy combinated with Super Gamma Knife, Super Gamma DT 16 -20Gy, 1 times/day, 2Gy/times. Results: Of 60 patients CR was 40% , PR 51.67% , SD 8.33 % , no PD case. Total effective 91.67%. 1, 2, 3 year survival rates 96.67% , 70% , 28.33%. The side reaction and complication were low. Conclusion; It is more effective in treatment of advanced cervical cancer by radiation therapy combined conventional super gamma knife, with less side effects, simpl, easy to be acceptted.%目的:探讨全盆腔常规放疗加分次立体定向伽玛刀治疗宫颈癌的疗效.方法:60例中晚期宫颈癌患者采用全盆腔常规放疗46-50Gy,加分次立体定向伽玛刀治疗,伽玛刀DT 16-20Gy,2Gy/次,1次/日.结果:近期疗效CR 40％,PR 51.67％,SD 8.33％,无PD病例.总有效率91.67％.1、2、3年生存率96.67％、70％、28.33％.近期毒副反应及远期并发症低.结论:全盆腔常规放疗加分次立体定向伽玛刀治疗中晚期宫颈癌疗效好,不良反应小,方法简便,易被患者接受.