Objective To investigate the prevalence and characteristic of the human parvovirus B19(B19) infection among women reproductive age. Methods B19-IgM antibody was detected by using enzyme linked immunosorbent assay method in the serum. Results Among the 10 125 cases,the overall infection rate of B19 was 13. 04％,and that were 12. 20％,13. 18％and 13. 68％ respectively in the past three years (P＞0. 05). The infection rate of B19 in women with abnormal outcome ,pregnant women and pre-marital care were 17. 34％ ,12. 61％ and 10. 82％ ,respectively (P＜0. 01). The ratio of abnormal outcome in the un-infected group had significant difference,as compared with those in the infected group (P＜0. 01).Conclusion The infection rate of B19 in women was high in Nanning. The surveillance of human Parvovirus B19 infection among women reproductive age should be performed.%目的 了解南宁地区育龄妇女人微小病毒B19(B19)感染状况及特点.方法 用酶联免疫吸附法检测2008～2010年南宁地区育龄妇女血清B19-IgM抗体,比较不良妊娠结局、妊娠和婚检妇女感染率及各年、季度感染情况.结果 10 125例育龄妇女,B19感染率为13.04%,不良妊娠结局组、妊娠组和婚检组感染度分别为17.69%,12.61%和10.82%,三组间感染率差异有统计学意义(P<0.01).各年感染率分别为12.20%,13.18%和13.68%,各年、季度感染率差异无统计学意义(P>0.05).感染组与非感染组不良妊娠结局发生率差异有统计学意义(P<0.01).结论 南宁地区育龄妇女B19感染率较高,应加强育龄妇女B19感染监测.
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