糖尿病合并皮肤及软组织感染的病原菌分布及耐药性分析

摘要

Objective:To analyze the distribution and drug resistance of pathogenic bacteria in diabetes with infections of skin and soft tissue .Methods:Bacteria identification and drug sensitivity test of 364 strains who were separated from infectious skin and soft tissue in hospitalized patients with diabetes were retrospectively analyzed .Results:The number of positive cultures of 364.Gram -positive cocci were for 42.86%,the most bacteria were staphylococcus aureus and staphylococcus epidermidis , the drug resistance rates of penicillin was higher .The Gram -negative cocci were for 47.25%, the most bacteria were pesudomonas aeruginosa and klebsiella , the drug resistance rates of ampicillin were 95.5%and 87.5%respectively .Conclusion:There is a high rate of skin and soft tissue infection in diabetes , and the drug -resistance of pathogens is higher .we should choose sensitive drugs depending on drug sensitivity test .%目的：对糖尿病合并皮肤及软组织感染的相关情况进行分析，以了解病原菌的分布及耐药性。方法：对我院确诊糖尿病患者合并皮肤及软组织感染部位分泌物分离出的364株病原菌分布及耐药性进行分析。结果：364株病原菌革兰阳性球菌检出率42.86％，其中主要2种致病菌为金黄色葡萄球菌和表皮葡萄球菌，对青霉素类的耐药率较高；分离出的革兰阴性杆菌检出率47.25％，其中2种主要致病菌为铜绿假单胞菌和克雷伯菌属，对于氨苄西林的耐药率最高，分别为95.5％和87.5％。结论：糖尿病患者合并皮肤及软组织感染率较高，且病原菌耐药性高，应根据药敏结果合理用药。