外阴阴道假丝酵母菌病伴发支原体及沙眼衣原体感染的研究

摘要

Complicated infection of vulvovaginal candidiasis(VVC)with mycoplasma / chlamydia trachomatis(CT) was investigated,choosing 86 female patients with recurrent VVC(RVVC),219 female patients with simple VVC and 200 health examining females who underwent ureaplasma urealyticum(Uu),mycoplasma hominis(Mh)and CT detection. Candida in vaginal discharge from all women with VVC was identified by fungal culture. The rates of Uu positive,Mh positive and mixed positive in both RVVC group and simple VVC group were significantly higher than those in control group respectively(P < 0. 05). Comparison of positive rates of CT among RVVC group,simple VVC group and control group,all the difference had no statistical significance(P > 0. 05). The positive rate of Uu was sig-nificantly different between positive and negative fungal culture groups(P < 0. 05),while the positive rate of CT had no significant difference between the two groups(P>0. 05). The infection rate of Uu in patients with VVC was signif-icantly higher than that in normal population,suggested that Candida mixed with infection of Uu would lead to the oc-currence of VVC,especial the recurrence of VVC.%为研究外阴阴道假丝酵母菌病（Vulvovaginal Candidiasis，VVC）患者合并支原体和衣原体感染情况，对86例复发性 VVC（recurrent Vulvovaginal Candidiasis，RVVC）患者、219例单纯性 VVC 患者以及健康妇女200例，分别进行解脲脲原体（Ureaplasma urealyticum，Uu）、人型支原体（ mycoplasma hominis，Mh）和沙眼衣原体（Chlamydia trachomatis，CT）检测；所有 VVC 病例均进行真菌培养。RVVC 组和单纯 VVC 组与对照组之间 Uu、Mh 及 Uu 混合 Mh 阳性率比较，差异均有统计学意义（P 约0.05）。而三组之间 CT 和 CT 混合支原体阳性率比较，均无显著性差异（P 跃0.05）。真菌培养阳性组与阴性组之间，Uu 阳性率比较有显著性差异（P 约0.05），而CT 阳性率比较无显著性差异（P 跃0.05）。结果表明，VVC 患者合并 Uu 感染较正常人群明显增高，假丝酵母菌与 Uu 混合感染可能导致 VVC 的发生和复发。