二甲双胍联合能量摄入限制治疗非酒精性脂肪肝疗效观察

摘要

Objective :To observe the metformin combined with energy intake restriction and treatment of non-alcoholic fatty liver .Methods :78 patients with non-alcoholic fatty liver patients were divided into two groups ,were given met-formin and polyene phosphatidyl choline capsules (Essentiale) treatment ,observed two sets of monthly treatment effect after the end of treatment biochemical markers and liver B .Results:The patients in the improvement of clinical symptoms ,liver function improved ,the total effective rate was no significant difference (P>0 .05) ,lipids decreased and liver B-improvement rate differences (P<0 .05) ,adverse reaction rates than is low .Conclusion:Metformin joint energy intake control efficacy in patients with treatment of nonalcoholic fatty liver ,security ,and have some effect in lowering blood pressure .%目的：观察二甲双胍联合能量摄入限制治疗非酒精性脂肪肝的疗效。方法：将78例非酒精性脂肪肝患者分为两组，分别给予二甲双胍和多烯磷脂酰胆碱胶囊（易善复）治疗，观察两组每月治疗效果及疗程结束后所有生化指标及肝脏B超。结果：两组患者在临床症状改善、肝功能好转上、总有效率无显著差异（P＞0．05），血脂下降和肝B超改善率有差异性（P＜0．05），不良反应发生率均较低。结论：二甲双胍联合能量摄入控制治疗非酒精性脂肪肝患者疗效、安全性好，且在降血脂方面有一定效果。