郭氏清胰汤不同给药途径治疗急性胰腺炎的临床对比研究

摘要

目的：探讨郭氏清胰汤空肠滴注对急性胰腺炎（Acute Pancreatitis ，AP）患者的治疗效果。方法：将2013年10月－2015年10月我院收治的96例A P患者随机分为实验组（郭氏清胰汤空肠滴注组）49例和对照组（郭氏清胰汤经胃给药组）47例。全部病例在西医治疗的同时，实验组通过手法盲插放置鼻空肠管进行空肠内滴注治疗，对照组采用传统鼻胃管给药，比较两组临床疗效及改良CT 严重指数（MCTSI）评分、细胞因子含量等指标，经统计学处理分析空肠滴注清胰汤的治疗效果。结果：实验组并发症发生情况及患者恢复时间均低于对照组（P＜0．05）；治疗后实验组血、尿淀粉酶值、MCTSI评分及细胞因子含量均低于对照组（P＜0．05）。结论：中药汤剂经空肠内滴注给药具有起效快、经济实惠、疗效稳定等优越性，作为AP患者一种新的给药途径，值得临床推广。%Objective :To evaluate the efficacy of acute pancreatitis (AP) with trans‐jejunum feeding Guo Qing Yi Tang (GQYT) .Methods :96 patients with AP were divided into therapy group and control group(47 patients) .All the pa‐tients were treated with common western medicine ,49 patients with trans‐jejunum feeding GQYT were selected for therapy group ,and the other 47 patients were treated by GQYT gastric infusion for control group .Then the two groups were compared with clinical efficacy ,modified CT severity index (MCTSI) score and cytokine content to analyze the efficacy of trans‐jejunum feeding GQYT .Results:(1)The therapy group is more effective than the control group in recovery and complication(P<0 .05) .(2)After treatment ,the value of the BAMS ,UAMS ,the modified CT severity in‐dex(MCTSI) score and cytokine content of the therapy group is lower than the control group (P<0 .05) .Conclusion:Trans‐jejunum feeding is regarded as a new route of administration with its superiority of quick and stable efficacy .