67例腹膜透析相关性腹膜炎患者临床特点分析

摘要

Objective :The aim of this study was to investigate the distribution and drug resistance of bacteria in 67 pa‐tients of peritoneal dialysis correlative peritonitis .As well as the clinical characteristics in Single Infection (SI) ,Multi‐ple Infection 1 (MI1) ,Multiple Infection 2 (MI2) groups was analyzed .Methods :A retrospective analysis with the in‐fection of 67 patients with peritoneal dialysis correlative peritonitis was carried out ,as well as the clinical character differences in different groups .Results:The major infective bacteria were Gram positive bacteria .In Gram positive bac‐teria the highest resistant percentage drug was penicillin G ,and in Gram negative bacteria was ampicillin .In SI ,MI1 , MI2 groups ,the white blood cell (WBC) of ascites on first day decreased .Thrombocyte (PLT ) and thrombocytocrit (PCT) decreased slowly .However the mean platelet volume (MPV) ,platelet distribution width (PDW) ,percentage of large thrombocyte (P‐LCR) was increased significantly ,as well as the albumin .All the P value were lower than 0 .05 . Conclusion:The major infective bacteria were Gram positive bacteria .The WBC in ascites and WBC ,PLT ,PCT ,MPV , PDW ,P‐LCR in peripheral blood may be used to predict multiple infections .%目的：分析67例腹膜透析相关性腹膜炎患者感染菌分布及耐药情况，并比较单发感染（Single Infection ，SI）、多发感染1（Multiple Infection 1，MI1）、多发感染2（Multiple Infection 2，MI2）组临床特点间的差异。方法：回顾性分析67例腹膜透析腹膜炎患者感染情况，并分析不同感染组间临床特点的差异。结果：腹膜透析相关性腹膜炎感染菌以革兰氏阳性菌为主。革兰阳性菌对青霉素G耐药率最高，革兰阴性菌对氨苄西林耐药率最高。S I、M I1、M I2各组间，第1天腹水常规白细胞逐渐下降。血小板、血小板压积逐渐减少，而血小板体积、血小板分布宽度、大型血小板比例逐渐增大。白蛋白水平逐渐增加。以上 P值均＜0．05。结论：腹膜透析相关性腹膜炎感染菌以革兰氏阳性菌为主。腹水常规白细胞、血常规白细胞、血小板、血小板压积、血小板体积、血小板分布宽度、大型血小板比例等可预测多发性腹膜炎的发生。