颅骨缺损患者脑血流改变对神经功能的影响

摘要

目的 探讨颅骨缺损患者颅内血流动力学对神经功能的影响.方法 将22例神志清楚的颅骨缺损患者术前行经颅多普勒超声( transcranial doppler sonography ,TCD) 及神经功能评分,术后复查TCD及神经功能评分,分析不同颅骨缺损时间、缺损面积患者颅内血流及神经功能的变化. 结果 缺损时间<6个月( 12例)与缺损时间>6 个月( 10例)患者在术、前术后TCD,术后KPS评分比较,差异有统计学意义;颅骨缺损面积大小对患者神经功能影响差异无统计学意义. 结论 颅骨缺损时间长短对患者颅内血流动力学有不同影响,颅骨缺损时间较短的患者脑血流影响较小,颅骨修补术后血流动力学改善较好,神经功能恢复较好.%Objective To study the effects of intracranial hemodynamics on neurological function of patients with skull defects . Methods Twenty two cases of the conscious patients with skull defects were checked with Transcranial Doppler Sonography (TCD) and evaluated neurological functional score before operation .The cases were reviewed the TCD and neurological functional score after operation and were analyzed the changes of intracranial blood flow and neurological functions in different time and area on patients with skull de -fects.Results The patients with skull defect in less than 6 months (12 cases) and the ones more than 6 months (10 cases) had statisti-cally significantly TCD before and after operation、KPS scores after operation;the skull defect area was not statistically effect on neurologi-cal functions in patients .Conclusion Skull defect length have different effects on patients with intracranial hemodynamic .The patients with shorter skull defect have fewer effects on cerebral blood flow .After cranioplasty , the intracranial hemodynamics changed better than before operation , and neurological functions recovered much better than before .