3.0T磁共振弥散加权成像在胰腺癌中的应用价值

摘要

Objective: The purpose of this study was to investigate the value of breath-holding diffusion-weighted MR imaging at 3. 0 T in pancreatic carcinoma. Methods: 30 normal volunteers and 30 patients with pancreatic cancer proven by histopathology underwent breath-holding diffusion-weighted MR imaging without fat suppression before operation, based on SE-EPI sequence and b values = 0 and 600 s/mm2 ADC values were statistically investigated and compared among pancreatic cancer, normal pancreas, and distal pancreatitis. Results:The ADC value of pancreatic cancer was the lowest, then followed by normal pancreas and distal pancreatitis, and there were statistical differences among them by ANOVA ( F = 18. 716, P =0. 0004) ; ADC value of pancreatic cancer was statistically lower than that of normal pancreas or distal pancreatitis ( P =0. 00483 and P =0. 00191 respectively). Conclusion: Breath-holding DWI at 3. 0 T helps to detect the lesion, and its ADC value can better disclose histopathological state in pancreatic cancer, normal pancreas and distal pancreatitis.%目的:分析评价在3.0T磁共振非脂肪抑制憋气DWl序列在胰腺癌中的应用价值.方法-30例正常志愿者与30例经手术病理证实的胰腺癌患者,在3.0T磁共振上,术前行基于SE-EPI的非脂肪抑制憋气DWI序列,b值为0和600s/mm2,统计学比较分析正常胰腺、胰腺癌及远端炎症区的ADC值.结果:不同组织的ADC值从低到高依次为胰腺癌、正常胰腺、远端炎症,单因素方差分析显示不同组织的ADC值有明显统计学差异,F值为18.716,P值为0.0004,两两比较分析显示胰腺癌分别与正常胰腺及远端炎症的ADC值统计学有明显差异,P值分别为0.00483及0.00191.结论:在3.0T磁共振上,非脂肪抑制憋气DWI序列有助于病灶筛查,其ADC值能够较好的反映胰腺癌、正常胰腺及远端炎症的组织病理状态.