Objective To compare the diagnostic value of local strain ratio method (LSR) and entire strain rate ratio method (ESR) in detecting benign and malignant breast tumor .Methods The elastography of 134 patients confirmed by pathology with 189 solid lesions evaluated by real-time ultrasound were diagnosed as 139 benign and 50 malignant by pa-thology .Receiver operating characteristic (ROC) curves were done to assess the diagnostic value of the elasticity rate of LSR and ESR .Results The areas under the ROC curve (AUC) of the LSR were 0 .932 and ESR 0 .866 .There were sig-nificant differences between the LSR and ESR .When the entire elasticity ratio was 3 .14 ,the sensitivity was 86 .2% ,the specificity was 81 .29% ;and the local elasticity ratio was 31 .14 ,the sensitivity was 96 .02% ,the specificity was 90 .02% . Conclusion LSR is more value than ESR in diagnosing benign and malignant breast lesions .%目的：探讨局部应变率比值（LSR）与整体应变率比值（ESR）对乳腺良恶性肿瘤的诊断价值。方法134例患者经手术病理证实189个病灶（良性139个，恶性50个）进行实时弹性成像定量检查，绘制病灶整体与局部弹性应变率比值的ROC曲线，比较两种模式的价值。结果 ESR的ROC曲线下面积（area under the curve ，AUC）为0．866，最佳临界点为3．14，敏感度、特异度、分别为86．2％（43/50）、81．29％（113/139）。L S R的A U C为0．932，最佳临界点为31．14，敏感度、特异度分别为96．02％（48/50）、90．02％（125/139），两者的差异有统计学意义（ P ＜0.01）。结论 LSR比ESR对乳腺良恶性肿瘤具有更高的诊断价值。
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