预注麻黄素、间羟胺预防脊麻后剖宫产孕妇低血压的效果及对新生儿的影响

摘要

Objective:To probe into the effect and influence of pre-injection of ephedrine and metaraminol on the newborn and prevention of maternal hypotension after cesarean section.Methods:120 cases of single-ton pregnancy underwent the spinal anesthesia for cesarean section in a hospital from January 2015 to January 2016 were chosen as research objects,who were divided into the control group and the observation group, with 60 patients in each group.Then the hypotension,nausea,vomiting,chills,number of palpitation and chest tightness of the pregnant and umbilical artery blood pH value during the cesarean section were recor-ded.Results:In the control group,there were 23 cases of maternal hypotension,while in the observation groupwere 3 cases;the incidence of nausea,vomiting,palpitation and chest tightness of two groups of ma-ternal were significantly different,and the different had statistical significance (P<0.05);the pH value of the pregnant women in the control group was lower than that of the observation group,and there was statis-tical significance (P<0.05).Conclusion:The metaraminol in the cesarean section after spinal anesthesia can more effectively prevent the occurrence of low blood pressure,which can significantly reduce the incidence of side effects,and there is no harm to the newborn,which is conducive to the protection of the life and safety of mother and infant.%目的：：探讨剖宫产脊麻后预注麻黄素、间羟胺对预防产妇低血压的效果及对新生儿的影响。方法：采集某院2015年1月~2016年1月期间行脊麻剖宫产术的孕足月单胎初产妇120例，分为对照组和观察组，各60例，记录各组产妇剖宫产术中低血压、恶心、呕吐、寒战、心慌胸闷的次数，新生儿脐动脉血pH 值。结果：对照组产妇出现低血压23例；观察组产妇出现低血压3例；两组产妇间的恶心、呕吐、心慌胸闷发生率差异显著，均有统计学意义(P<0.05)；对照组产妇新生儿的 pH 值低于观察组，有统计学意义(P<0.05)。结论：间羟胺较麻黄素在产妇剖宫产脊麻后能更有效预防低血压的发生，明显减少副反应的发生，且对新生儿也没有危害，有利于保护母婴的生命安全。