畸形子宫早孕药物流产的临床观察

摘要

Objective:To investigate the clinical effect of drug induced abortion in abnormal uterine preg-nancy (the uterine septum,uterus bicornis,bicorbate uterus and uterus unicornis).Methods:37 patients with abnormal uterine pregnancy received drug induced abortion (mifepristone combined with misoprostol) termination of pregnancy.Results:Among the 37 patients,28 patients were complete abortion,8 patients were incomplete abortion,1 case was abortion failure.Incomplete abortion and abortion failure patients un-derwent curettage,the postoperative course was uneventful,no accidents such as uterine perforation or suc-tion leaks occurred.The complete abortion rate was 75.7%,the curettage rate was 24.3%.Conclusion:The success rate of drug induced abortion in abnormal uterine pregnancy is high,and for incomplete abortion and medical abortion failure patients,because early drug effects enable embryo stripping,uterine contraction ex-trusion blastocyst and uterine luminal contents of depression or partial discharge,it can effectively reduce the risk of abortion.%目的：：针对药物流产终止畸形子宫(子宫纵隔、双角子宫及鞍状子宫、单角子宫)早孕的临床效果展开探讨。方法：37名畸形子宫早孕患者用药物流产(米非司酮联合米索前列醇口服)终止妊娠。结果：37名患者中完全流产28名，未完全流产8名，流产失败1名。而后为不全流产及流产失败患者均行清宫术，手术过程顺利，未产生子宫穿孔、漏吸等情况。完全流产率为75.7%，清宫率为24.3%。结论：畸形子宫早孕应用药物流产成功概率较高，对不全流产及药流失败者因前期药物作用使胚胎剥离，子宫收缩挤压胚囊及宫腔内容物下移或部分排出，可有效降低清宫术的风险。