目的:了解女性生殖道感染者的支原体感染状况及耐药性, 为临床治疗提供实验依据, 减少抗生素的滥用.方法:采用珠海迪尔公司试剂盒, 对我院2 897例疑似生殖道感染患者的标本进行支原体培养及药敏实验检测.结果:2 897例患者中2 265例支原体阳性 (78.2％), 其中Uu阳性者1 536例 (53.1％), Mh阳性者68例 (2.3％), Uu+Mh阳性者661例 (22.8％) .药敏实验显示, 对支原体敏感性高的抗生素分别为强力霉素、交沙霉素、美满霉素、四环素;耐药性高的药物分别为红霉素、左氧氟沙星、氧氟沙星、环丙沙星.结论:女性生殖道感染以Uu感染为主, 其耐药形势严峻, 临床治疗支原体感染应以药敏试验为依据, 合理选择抗生素;对于多耐菌株可探索中药治疗途径, 中西医结合降低细菌耐药率, 提高临床治愈率.%Objective:To analyze the infection and drug resistance of mycoplasma in female genital tract aiming to provide reliable experimental basis for clinical treatment and reducing bacterial resistance.Methods:2 897 cases with suspected reproductive tract infections were detected with Mycoplasma culture and drug sensitivity test using Zhuhai Deere Company kit.Results:The positive numbers of Mycoplasma were 2 265 (78.2％) among the 2 897 sample;1 536 cases (53.1％) were Uu positive;68 cases (2.3％) were Mh positive;661 cases (22.8％) were both Uu and Mh positive;the high susceptibility to 12 antimicrobial drugs in sequence were DOX, JOS, MIN, TET;the high resistance drugs in sequence were ERY, LEV, OFL, CIP.Conclusion:Uu infection is the main type in female genital tract infections and the situation of drug resistance is severe.The treatment of mycoplasma infection should based on the susceptibility test and rational selection of antibiotics.The treatment of multi-resistant strains may use Traditional Chinese Medicine, and integrated Traditional Chinese and Western Medicine may reduce the bacterial resistance rate, improve the clinical cure rate.
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