A group of immature myeloid-derived cells called Myeloid-derived suppressor cells ( MDSCs) which involved in tumor proliferation, invasion and pathological processes, and promote tumorigenesis and growth;and the tumor microenvironment may also in-duce MDSCs further proliferation.This article will do a review about the MDSCs on the generation and interaction between tumor and part of the mechanism.%髓系来源抑制细胞( Myeloid-derived suppressor cells,MDSCs)是一群未成熟的髓系来源细胞,参与了肿瘤的增殖、侵润、肿瘤血管生成、免疫抑制等病理过程,促进肿瘤的发生和生长;反过来,肿瘤以及肿瘤微环境也可促使MDSCs进一步增殖。本文就MDSCs的产生以及和肿瘤之间的相互作用以及部分作用机制做一综述。
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