基于“肺主悲忧”理论探讨慢性阻塞性肺疾病合并抑郁∗

摘要

Chronic obstructive pulmonary disease (COPD) is one of common respiratory diseases,with high incidence and mortality rate,which is the fourth leading cause of death in the worldwide. Thus, more and more attention has been paid to COPD. Due to COPD triggered the PHT ,cor pulmonale and other complications easily, patients unders recurrent pulmonary infection, lung function decline, prolonged prescribing, weighty economy burden, they are more liable to have bad mood such as anxiety, depression. Deeply disturbed by bad feelings, poor compliance. It was hard to cooperate with the treatment of medical staff and lead to disease with poor prognosis, reinforcing a vicious cycle. ? However there was a shortage of clinical research and experimenta study on COPD combined with depres-sion. The mechanism behind this was not fully understood. The author tried to explore the mechanism of COPD combined with depres-sion from the principal of the lung governs sorrow. So more new ideas and paths were provided for the treament of COPD with depres-sion.%慢性阻塞性肺疾病是一种常见肺部疾病，发病率及病死率高，占全球死亡原因的第四位，因此深受社会关注。由于慢性阻塞性肺疾病容易诱发肺动脉高压、肺源性心脏病等各种并发症，且此类病人反复肺部感染，肺功能下降，长期服药，社会经济负担重等诸多因素极易引发焦虑、抑郁、悲观等不良情绪。而深受不良情绪困扰，社会依从性差，难以配合医护人员的治疗又会导致疾病预后差，形成恶性循环。而目前对慢阻肺合并抑郁的实验研究及临床研究都比较缺乏，相关机制不完全清楚，试图从“肺主悲忧”角度去探讨慢阻肺合并抑郁的发病机制，为慢阻肺合并抑郁的治疗提供更多的思路和途径。