Objective To investigate the perioperative risk and short-term efficacy of balloon-expandable stent implantation in treating severe arterial stenosis located at the origin of vertebral artery. Methods During the period from Jan. 2010 to Sep. 2011, a total of 27 patients with 29 symptomatic arterial stenosis (≥ 70%) which was located at the origin of vertebral artery were treated with balloon-expandable stent implantation after they had failed to respond the conventional medication for ischemia symptoms. The patients were followed up at 1, 3, 6, 9 and 12 months after the treatment. The blood cholesterol, blood sugar, blood pressure were estimated. Arterial ultrasonography was reexamined 6 months after the treatment, and DSA was performed at 12 months after the therapy. The results were analyzed. Results Stent implantation was successfully accomplished in all 27 patients. The mean stenosis ratio decreased from preoperative (92.55 ± 5.26)% to postoperative (3.27 ± 4.6)%. No procedure-related complications occurred. Clinical followed-up was conducted for 12 months after the procedure, and no ischemia events of posterior circulation occurred. No in-stent restenosis or stent deformation was observed. Conclusion For the treatment of severe arterial stenosis located at the origin of vertebral artery balloon-expandable stent implantation is safe and effective with fewer complications and satisfactory short-term efficacy.(J Intervent Radiol, 2012, 21: 270-273)%目的 探讨采用球囊扩张支架治疗椎动脉起始部重度狭窄的围手术期风险及短期预后.方法 2010年1月- 2011年9月收治27例后循环缺血患者,29处症状性椎动脉起始部狭窄率≥70％,因常规药物治疗无效,采用球囊扩张支架进行治疗.术后1、3、6、9、12个月进行随访,监测血脂、血糖、血压.术后6个月复查动脉超声,12个月时复查DSA.结果 27例患者的29处重度狭窄均成功置入球囊扩张支架,技术成功率100％.术前狭窄率80％～ 99％,平均92.55％±5.26％,中位狭窄率95％:术后狭窄率0％～ 15％,平均3.27％±4.60％,中位狭窄率0％,手术并发症0.术后随访12个月时,无后循环缺血事件发生.12个月时随访DSA,支架内内膜增生l例,再狭窄0例.结论 应用球囊扩张支架治疗椎动脉起始部重度狭窄围手术期并发症发生率低,短期预后良好.
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