高海拔地区部分脾动脉栓塞术治疗脾功能亢进临床分析

摘要

目的 探讨高海拔地区部分脾动脉栓塞术(PSE)治疗脾功能亢进(脾亢)的临床效果及意义.方法回顾性分析2015年3月至2016年12月采用PSE术治疗的青海省西宁市地区66例肝硬化门静脉高压性脾亢患者临床资料,分别于术前1 d及术后1、7、30、90 d检测患者白细胞(WBC、红细胞 (RBC)、血小板(PLT)计数变化.结果PSE术技术成功率为100％.66例患者PSE术后1、7、30、90d平均WBC计数与术前1 d比较,差异均有统计学意义(P＜0. 05);术后1、7、30、90 d平均PLT计数与术前1 d比较,差异均有统计学意义(P＜0. 05).结论PSE术治疗高海拔地区脾亢患者疗效肯定,值得临床推广.%Objective To investigate the clinical curative effect and significance of partial splenic artery embolization (PSE) for the treatment of patients with hypersplenism at high altitude region. Methods The clinical data of 66 patients with cirrhosis complicated by portal hypertension and hypersplenism, who lived in Xining City of Qinghai Province, the high altitude region in China, and were admitted to authors' hospital during the period from March 2015 to December 2016 to receive PSE, were retrospectively analyzed. White blood cell (WBC) count, red blood cell (RBC) count and platelet (PLT) count were calculated at one day before operation as well as at one, 7, 30 and 90 days after operation. Results The technical success rate of PSE was 100％. The mean WBC count determined at one, 7, 30 and 90 days after PSE was obviously different from that determined at one day before PSE, the differences were statistically significant (P＜0. 05). Conclusion For the treatment of patients with cirrhosis complicated by portal hypertension and hypersplenism, who live at high altitude region, PSE has reliable curative effect, therefore, this therapy is worth promoting in clinical practice. (J Intervent Radiol, 2018, 27: 271-273)