输卵管上皮内癌为隐性癌,在乳腺癌易感基因( BR CA)突变患者中行预防性双附件切除时发现,其病因不明,人群中发病率不详,在BRCA基因突变患者中其发病率为4.4％～8％,且可早期出现腹腔冲洗液细胞学阳性及盆腔种植转移.对于卵巢癌的起源问题,现仍有争议,认为卵巢癌有两种起源方式,其中高分化浆液性癌被认为是起源于输卵管.输卵管上皮内癌多无症状,早期诊断困难,即使行双附件切除后,仍需仔细行全部输卵管病理检查才能发现,所以临床易漏诊.治疗与卵巢癌相同,输卵管上皮内癌会越来越引起人们的重视.%Tubal intraepithelial carcinoma is occult,which can be found in prophylactic salpingo-oophorectomies from women with BRCA mutations. Etilogy and the incidence of population is unknown. The incidence of women with BR-CA mutations is 4.4%~8%. Positive peritoneal washings and pelvic implanted metastasis may appeared. The origin of the ovarian cancer has been debated. There are two ways of origin of ovarian cancer. High-grade serous carcinoma has been considered from fallopian. Tubal intraepithelial carcinoma has been diagnosed difficultly because of no early symptoms. Fallopian be required carefully checking after prophylactic salpingo-oophorectomies. Otherwise tubal intraepithelial carcinoma can be missed. Therapy is similar with ovarian cancer. We must attach importance to tubal intraepithelial carcinoma.
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