低频电刺激对健康成年人体感和运动诱发电位的影响

摘要

Objective: to observe the effects of low-frequency electrical stimulation (LES) on healthy adult with somatosensory evoked potential (SEP) and motor evoked potential (MEP). Method: 25 healthy adults (thirteen males and twelve females, with a mean age of 42.9 and a standard deviation of 5.7) participated in the study. SEP and MEP were measured before and after the LES stimulation. Results: After LES, the latency of SEP and MEP for the stimulated side became shorter and the amplitude became greater. These changes in latency and amplitude were statistically significant (P<0.05). For the unstimulated side, the changes of SEP and MEP did not show statistically significant difference. Conclusion: The SEP and MEP parameters, especially the amplitude, can be used to evaluate the effect of LES on central nervous system (CNS).%　　目的：观察低频电刺激(Low-frequency Electrical Stimulation，LES)对健康成年人体感诱发电位(Somatosensory Evoked Potential，SEP)及运动诱发电位(Motor Evoked Potential，MEP)的影响。方法：入选25例健康成年人(男13例，女12例，平均年龄42.9±5.7岁)，采用经颅磁刺激仪(TMS)及肌电图仪，分别测量 LES 刺激前后 SEP 值及 MEP 值。结果：健康成年人 LES 刺激后 SEP 及 MEP 值的潜伏期缩短、波幅增高，与刺激前比较，差异有统计学意义(P<0.05)；非刺激侧无明显变化。结论：健康成年人 LES 刺激前后 SEP 及 MEP 参数值均有显著性变化，尤以波幅明显，提示电刺激对中枢神经系统存在作用。