目的 总结分析同位素131Ⅰ治疗甲亢伴白细胞减少症利弊及其临床疗效及使用的安全性.方法 选择2008年以来我院接收的甲亢伴白细胞减少患者28例,随机分配为实验组(n=14)和对照组(n=14),实验组接受口服同位素131Ⅰ治疗,对照组接受口服抗甲状腺类药物治疗,6个月后对所有患者进行复诊.结果 治疗后6个月实验组患者体内白细胞数量明显增加,与治疗前相比差异有统计学意义(P＜0.05);实验组药物显效率与对照组相比差异有统计学意义(P＜0.05).结论 应用131Ⅰ治疗甲亢伴白细胞减少,其放射性对于骨髓的影响甚微,不至于引起白细胞的进一步降低,具有较好的临床疗效,是一种理想的治疗方法.%Objective To conclude and analye the clinical effect of radioiodine131I used in the treatment of hyperthyroidism with granulocytopenia. Mefhods 28 cases of patients with hyperthyroidism with granulocytopenia received by hospital since 2008 were randomly divided into experimental group (n=14) and control group (n=14).Experimental group were given the radioisotope 131I and control groups were given the anti-thyroid drugs. All patients were reexamined at 6 months after treatment. Results The number of leucocyte was significantly increased after 6 months in experimental group and showed significant difference(P＜0.05);The drug effective rate in experimental group were significantly different fiom that in control group (P＜0.05). Conclusion Radioisotope 131I used in the treatment of hyperthyroidism with granulocytopenia showed good clinical effect, As an ideal treating method, it' s deserved to be promotion clinically.
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