孕早期稽留流产的病因分析及清宫术后用药评价

摘要

Objective To analyze the main cause of missed abortion in early stage of pregnancy, and investigate the clini-cal value of Yixuean Keli after curettage. Methods The 150 cases of missed abortion patients admitted to our hospital from January 2014 to December 2015 were randomly divided into two groups, observation group(n=75)and control group(n=75). The control group was given clindamycin palmitate hydrochloride dispersible tablets in prevention of infection, the observa-tion group was also given Yixuean Keli. Through the information collection and clinical detection, the main causes of missed abortion would be analyzed; and the clinical efficacy after curettage in 2 groups were observed and compared. Results The top 5 causes of missed abortion were intrauterine inflammation of the vagina, pathogen infection, exposure to toxic and high radia-tion environment, lack of trace elements(zinc), genetic material change in 2 groups, the difference is not statistically significant between the groups; the vaginal bleeding days and the menstrual cycle in the observation group were significantly shorter than the control group; the endometrial thickness after curettage 2 weeks in the observation group were significantly thicker than the control group; the incidence of re-curettage, the uterine cavity inflammation and the intrauterine adhesion in the observation group were significantly less than the control group. Conclusion To prevent reproductive tract infections, apart from toxic and high radiation environment, correct zinc deficiency and endocrine abnormalities and other measures can reduce the occurrence of missed abortion in early pregnancy, and anti- inflammatory treatment after curettage of missed abortion in early pregnancy with Yixuean Keli conditioning, can promote the menstruation and the uterus of newborn, reduce intrauterine adhesions and in-flammation.%目的:统计分析孕早期稽留流产的主要病因,探讨清宫术后服用伊血安颗粒的临床价值.方法:2014年1月~2016年6月在本院行清宫术的150例孕早期稽留流产患者随机分成观察组(75例)和对照组(75例),对照组术后静滴克林霉素预防感染,观察组再给予伊血安颗粒调理.通过信息采集及临床相关检测,分析孕早期稽留流产的主要病因;比较清宫术后的用药效果.结果:两组的前5位病因均为阴道、宫腔炎症感染,病原体感染,接触有毒、高辐射环境,微量元素缺乏(锌),遗传物质改变,组间病因比较差异无统计学意义;观察组清宫术后的阴道出血天数、月经复潮时间明显短于对照组,观察组术后半个月的子宫内膜厚度明显大于对照组,观察组二次清宫、子宫内膜炎、宫腔粘连等不良反应发生率均明显少于对照组.结论:防治生殖道感染、远离有毒和高辐射环境、纠正锌缺乏和内分泌异常等措施可降低孕早期稽留流产发生,孕早期稽留流产清宫术后预防感染之外加用伊血安颗粒调理,可以促进月经复潮和子宫内膜新生,减少宫腔粘连和发炎.