层层自组装功能化涂层及其生物应用研究进展

摘要

层层自组装作为一种新颖的材料制备技术,具有制备条件可控,适用于多种物质,具备产业化前景等诸多优点.探讨层层自组装技术的优势及其近几年的生物医学应用(构建生物相容性界面,改性组织工程支架表面,药物载体的制备)和功能化涂层应用,重点详述用层层自组装技术制备功能化涂层并使其具有不同响应性的研究进展.%As a novel material preparation technology,the layer-by-layer (LBL) technique has many advantages,such as controlled preparation conditions;suitable for a variety of material and great industrialization prospects.This paper discussed the advantages of LBL self-assembly technology as well as its biomedical applications-synthesis of biocompatible interface,surface modification tissue engineering scaffolds,preparation of drug carrier-and functional applications,focusing on progress of the functional coatings and its different response.