Objective To study the prognostic factors of long - term survived patients with recurrent and metastatic breast cancer to guide the clinical treatment. Methods The clinical data of 82 recurrent and metastatic breast cancer patients from March 2006 to December 2010 were retrospectively analysed. A number of potential factors which might affect prognosis were evaluated by multivariate COX regression model and survival analysis was performed by Kaplan - Meier combining with Log - rank test. Results Univariate analysis showed size of tumor ^counts of metastatic lymph node of axilla and staging can affect the prognosis ( P <0. 05 ). However, in the Cox multivariate analysis, only counts of metastatic lymph node of axilla was significant prognostic factors which affect the prognosis ( P <0. 05 ). Conclusion The counts of metastatic lymph node of axilla is an independent prognostic factor in recurrent and metastatic breast cancer patients.%目的 分析复发转移性乳腺癌患者的预后相关因素,为临床治疗提供参考.方法 回顾性分析2003年3月-2010年12月复发转移性乳腺癌患者82例,通过比例风险模型(COX模型)进行多因素分析,生存分析采用Kaplan-Meier法并进行Log-rank时序检验.结果 单因素分析显示肿块大小、腋窝淋巴结转移数目对总生存期有显著影响(P＜0.05).但COX多因素分析显示只有腋窝淋巴结转移数目才是总生存期的独立预后因素(P＜0.05).结论 腋窝淋巴结转移数目可以作为独立的预后因素,对于预测复发转移性乳腺癌患者的总生存期和复发转移后生存期有重要的意义.
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