前列腺癌骨及精囊转移的MRI诊断研究

摘要

Objective:To study the value of MRI in the diagnosis of bone and seminal vesicle metastasis of prostate cancer,and to provide reference for clinical diagnosis.Methods:136 cases of prostate cancer treated in our hospital between December 2015 December 2017 were collected.MRI prostate and peripheral tissue,pelvic and spinal scan were performed before the puncture biopsy,and systematic biopsy of the prostate was performed at the end.The specificity,accuracy and sensitivity of MRI scan in the diagnosis of bone and seminal vesicle metastasis of prostate cancer were compared with the pathological diagnosis as gold standard.Results:the pathological diagnosis of 136 cases of prostate cancer occurred in 34 cases (25 ％),including 16 cases of seminal vesicle metastasis (10.3 ％),and 20 cases of bone metastases (14.7 ％).A total of 42 cases of metastasis (30.9 ％) were diagnosed by MRI,of which 20 cases (14.7 ％) were metastases of seminal vesicle and 22 cases of bone metastases (16.2％).The specificity of MRI for the diagnosis of prostate cancer seminal vesicle and bone metastases was 95.7％,the sensitivity was 76.2％,and the accuracy was 89.7％.Conclusion:compared with pathological biopsy,MRI has high specificity and accuracy in diagnosing seminal vesicle metastasis and bone metastasis in patients with prostate cancer,but the sensitivity is deficient.It is worth promoting in clinic.%目的:研究前列腺癌骨及精囊转移的MRI诊断价值,为临床精准诊断提供参考.方法:收集我院2015年12月～2017年12月收治的136例前列腺癌患者.穿刺活检前行MRI前列腺及周围组织、盆腔、脊柱扫描诊断,最后行前列腺系统性穿刺活检.以病理诊断为金标准,对比MRI扫描诊断前列腺癌骨及精囊转移的特异性、准确性及灵敏度.结果:136例前列腺癌患者病理诊断共发生34例(25.0％)转移,其中精囊转移16例(10.3％),骨转移20例(14.7％).MRI诊断共发生42例(30.9％)转移,其中精囊转移20例(14.7％),骨转移22例(16.2％).MRI诊断前列腺癌精囊及骨转移的特异度为95.7％,灵敏度为76.2％,准确度为89.7％.结论:与病理活检相比,MRI诊断前列腺癌患者精囊转移及骨转移特异度及准确度均较高,但灵敏度有所欠缺.