实验性轻度病毒性心肌炎的组织病理学观察

摘要

To study the diagnostic method of slight viral myocarditis in the field of forensic pathology, slight viral myocarditis model was induced in Balb/c murine by coxsackie virus B3. Organs of hearts, livers, spleens, lungs and kidneys were examined through routine pathological methods. Pathological changes at different levels of these organs were observed. The results indicated that viral myocarditis was a kind of disease with multiple organ alterations and that the pathological observation and comprehensive analysis of multiple organs was one of the useful methods for diagnosing slight viral myocarditis.%为探索轻度病毒性心肌炎的法医病理学诊断方法，以适量CoxsackieB3病毒感染Balb/c小鼠造成小鼠轻度病毒性心肌炎，对病鼠的心、肝、脾、肺、肾进行常规病理学检查。结果发现，心肌炎小鼠的各器官出现不同程度的病理改变。实验提示，病毒性心肌炎是一类多器官病变的疾病；对多器官进行病理学观察和综合分析是轻度病毒性心肌炎的组织病理学诊断的有效方法之一。