养阴解毒汤治疗急性放射性食管炎临床观察∗

摘要

Objective:To study the clinical effect of Yangyinjiedu Decotion on esophagitis caused by radiation. Methods:62 cases of esophageal malignancies who would accept conventional radiotherapy were randomly divid⁃ed into treatment group and control group. All patients were treated by IMRT(60 Gy/30 f). Patients in the for⁃mer were given Yangyinjiedu Decoction during radiotherapy,while those in the latter treated with compounds of rhG-CSF+lidocaine+dexamethasone during radiotherapy. The clinical effects of the two groups were observed. Results:Incidence rates of esophagitis of the treatment were less than that of control group(P<0.05). The ef⁃fect rate of the treatment group was 95.20%,while that of the control group was 67.86%(P<0.05). Conclusion:Yangyinjiedu soup was effective on esophagitis caused by radiation,it was worth applying more widely.%目的：观察自拟养阴解毒汤治疗急性放射性食管炎的临床效果。方法将62例欲行常规放疗的食管肿瘤患者随机分为研究组和对照组，两组照射剂量均为60 Gy/30 f，均行调强放射治疗；研究组32例养阴解毒汤以沙参麦冬汤为底化裁而成，对照组30例以利多卡因加地塞米松加重组人粒细胞集落刺激因子混合溶液漱口，自放疗开始至放疗结束，进行疗效对照观察。结果研究组放射性食管炎的发病率明显低于对照组（P<0.05）；研究组有效率95.20%，明显高于对照组的67.86%（P<0.05）。结论养阴解毒汤防治放射性食管炎效果良好。