红花黄色素注射液联合左卡尼汀治疗老年冠心病稳定型心绞痛56例

摘要

目的 观察红花黄色素注射液联合左卡尼汀治疗老年冠心病稳定型心绞痛的临床疗效和安全性.方法 将112例老年冠心病稳定型心绞痛患者随机分为治疗组与对照组,各56例.对照组给予抗血小板聚集、硝酸酯类、钙拮抗剂及β受体阻滞剂等常规治疗,治疗组在常规治疗的基础上应用红花黄色素注射液联合左卡尼汀,两组均以7d为1个疗程,共治疗2个疗程.结果 治疗后,治疗组心绞痛、心电图总有效率均高于对照组(P＜0.05),血液流变学指标改善程度也优于对照组(P＜0.05),且两组不良反应发生率无明显差异(P＞0.05).结论 红花黄色素注射液联合左卡尼汀治疗老年冠心病稳定型心绞痛具有安全、有效的特点.%Objective:To observe the efficacy and safety of Safflower Yellow Injection combined with levocarnitine in treatment of stable angina in elderly patients.Methods:A total of 112 elderly patients with stable angina of coronary heart disease from May 2014 to May 2016 were randomly divided into treatment group (n =56) and control group (n =56).Both groups were treated with conventional treatment (including,anti-platelet aggregation,nitrates,calcium channel blockers and β3-R blockers).The treatment group was additionally treated with safflower yellow injection combined with levocarnitine.One course of treatment was 7 d,and the two groups were treated for 2 courses.Changes of angina pectoris,the total effective rate of electrocardiogram and hemorheology indexes,and adverse reactions in two groups were observed.Results:After a 2-course treatment,the values of angina pectoris and the total effective rate of electrocardiogram in treatment group were significantly higher than those of control group (P＜ 0.05);Hemorheology improvement in treatment group was superior to that of control group (P＜ 0.05),and there was no statistical difference on adverse reaction rate in two groups (P＞ 0.05).Conclusion:The treatment of stable angina in elderly patients with coronary heart disease with safflower yellow injection combined with levocarnitine is safe and effective,is worthy to be popularized in the clinical.