斑点追踪技术评价年龄因素对正常成人右房功能的影响

摘要

目的：应用斑点追踪（STE）技术评价年龄因素对正常成人右房功能的影响。方法选择146例体检健康者按年龄分为三组：Ⅰ组40例，年龄20～39岁；Ⅱ组55例，年龄40～59岁；Ⅲ组51例，年龄60～80岁。常规超声测量右房长径（RAL）、短径（RAS）及最大面积（RAAmax），三尖瓣口舒张早期峰速（TVE）、舒张晚期峰速（TVA）、三尖瓣环舒张早期速度（TVe’）和舒张晚期速度（TVa’）；STE测量右房6节段收缩期应变率（SRs）、舒张早期应变率（SRe）、舒张晚期应变率（SRa），并计算右房收缩期平均应变率（SRs-avg）、舒张早期平均应变率（SRe-avg）、舒张晚期平均应变率（SRa-avg）。结果 RAS、RAAmax随年龄增大而增大，SRs-avg、SRe-avg随年龄增大而减小（均P＜0．05），且SRs、SRe减小主要位于房间隔；SRa-avg随年龄增大而增大（P＜0．01），且SRa-avg增大主要位于房间隔。RAAmax与年龄呈正相关（r＝0．331， P＜0．05），SRs-avg、SRe-avg与年龄呈负相关（r＝-0．415、-0．227，均P＜0．05），SRa-avg与年龄呈正相关（r＝0．209，P＜0．05）。结论正常成人右房随年龄增大而增大，右房功能亦随增龄改变，其容量器功能、管道功能减低，泵功能增加，且房间隔受损显著。STE评价正常成人右房功能随年龄改变可行且有效。%Objective To determine effect of age on right atrial(RA)function by two-dimensional(2D)speckle tracking echocardiography(STE). Methods A total of 146 healthy volunteers were divided into three age groups(20~80 years). RA long axis diameter,RA short axis diameter,RA area,the peak velocity of the early diastolic filling wave(E-wave velocity), the peak velocity of the late diastolic filling wave(A-wave velocity),tricuspid annular velocity e’and a’.STE was used to measure peak strain rate of systole,early and late diastole(SRs,SRe,SRa)of right atria1 wall.The mean peak strain rates(SRs-avg,SRe-avg and SRa-avg)were calculated. Results RAS,RAAmax were increased with age (all P<0.05),SRs-avg,SRe-avg were decreased with aging (all P<0.05),SRa-avg was increased with age (P<0.01). Age had significant effect on SRs,SRe and SRa of atrial septum. RAAmax and SRa-avg were positively with age (r=0.331,0.209,P<0.05),but SRs-avg,SRe-avg was negatively correlated with age (r=-0.415,-0.227,P<0.05). Conclusion STE is a new method which can usefully and effectively measure the effect of age on RA function. In normal people,the RA function change with the increase of age.