快速康复外科应用于结直肠癌手术对患者应激反应的影响

摘要

目的 探讨快速康复外科应用于结直肠癌手术对患者应激反应的影响.方法 随机选取25例按常规方法进行围手术期处理的结肠癌患者作为对照组,和同期25例结肠癌患者应用FTS方案为FTS组,于术前、术后第1天、术后第5天晨检测血C-反应蛋白、白细胞介素-2及血清皮质醇的变化.结果 两组CRP、IL-2、Cor在术后第1天均较术前明显升高(P＜0.05),FTS组术后CRP、IL-2、Cor明显低于对照组(P＜0.05).结论 快速康复外科应用于结直肠癌手术较常规结直肠癌手术机体创伤小,应激水平低.%Objective To investigate the influence of fast track surgery(FTS)on colorectal cancer surgery patients with stress reactions. Methods Twenty-five colon cancer patients who underwent traditional perioperative management were randomly selected as the control group. During the same period, another 25 colon cancer patients who underwent FTS were selected as the FTS group. The levels of serum C-reactive protein (CRP) , interleukin-2 (IL-2) and cortisol ( Cor) were measured on the pre- operation day, the 1st day and the 5th day after surgery. Results The levels of CRP,IL-2 and Cor in both groups were elevated significantly in the first postoperative day. The levels of CRP,IL-2 and Cor in the FTS group were significantly lower than those in the traditional group. Conclusion In colorectal cancer surgery,FTS has the advantages of less trauma and lower stress responses compared with the traditional method.