目的：探讨在一系列的原发性神经内分泌肿瘤( NTLs)病例的关键影像学表现，特别是CT表现。方法分析评估22例病理诊断确诊的(NTLs)患者(12例男性，平均年龄60岁)影像学表现，描述侧重于计算机体层摄影在观察到的变化。结果5个典型类癌、3个非典型类癌、3个大细胞神经内分泌癌( LC-NCs)和11个小细胞肺癌( SCLCs)。只有一个典型类癌特征表现为中央支气管结节合并远端肺不张，而其他表现为的肺结节或肿块；非典型类癌对应了外围混杂密度肿块；3个 LCNCs 有一个是周围的均质肿块，其他则是边界不清和混杂密度；11个SCLCs 对应了中央的、浸润的和非均质肿块及继发的肺及胸膜改变，钙化未在 LGNCs 和 SCLCs表现。 LCNCs 和 SCLCs 的所有病例均在较早及后续随访观察发现转移。结论虽然一些成像特点可能类似，但影像学表现与临床信息可能在分别NTLs的组织学类型的发挥相关作用。%Objective To describe the key imaging findings in a series of cases of primary neuroendocrine tumors of lung ( NTLs) . Methods The imaging features of 22 patients were retrospectively analyzed, which inclu-ding 12 men and their mean age was 60 years old. Results There was only 1 case of entral endobronchial nodule with distal pulmonary atelectasis among 5 cases of typical carcinoids, 3 cases of atypical carcinoids, 3 cases of large-cell neuroendocrine carcinomas ( LCNCs) , and 11 cases of small-cell lung cancers ( SCLCs) . The others were pul-monary nodules or masses. The atypical carcinoids corresponded to peripheral heterogeneous masses. One out of the three LCNCs was a peripheral homogeneous mass, while the others were ill-defined and heterogeneous. The 11 SCLCs corresponded to central, infiltrating and heterogeneous masses with secondary pleuropulmonary changes. Calcifica-tions were absent both in LGNCs and SCLCs. Metastases were found initially and also at follow-up of all the cases of LCNCs and SCLCs. Conclusion Although some imaging features may be similar, radiologic findings considered to-gether with clinical information may play a relevant role in the differentiation of histological types of NTLs.
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