Objective To explore the insight status of community schizophrenics and its relationships to demographic characteristics, clinical features or quality of life.Methods Assessments were performed in 623 community schizophrenics using self-made information questionnaire, Brief Psychiatric Rating Scale (BPRS), Rating Scale for Extrapyramidal Side Effects (RSESE), Montgomery-Asberg Depression Rating Scale (MADRS), 12-Item Short Form Health Survey (SF-12) and Insight and Treatment Attitudes Questionnaire (ITAQ).Results 72.4% of the patients had good insight and 27.6% poor.There were significant differences in clinical aspects such as first-episode, course, hospitalization frequencies, used drugs and chlorpromazine equivalence as well as demographic data as onset ages and times of receiving an education among patients with different insights (P<0.05 or 0.01), but was no in quality of life (P>0.05).Regression analysis showed that independent influencing factors of insight were course, negative symptoms, refusing to taking drug and the utilization rate benzodiazepines (P<0.01).Conclusion Community schizophrenics have better insights, their insights are influenced by course and negative symptoms, and have nothing to do with quality of life.%目的 探讨社区精神分裂症患者自知力状况,及其与人口学特征、临床特征和生活质量的关系.方法 对623例社区精神分裂症患者采用自制资料调查表、简明精神病量表、锥体外系副反应评定量表、蒙哥马利抑郁评定量表、医疗结局研究表格、自知力和治疗态度问卷进行测评分析. 结果 本组72.4%的患者自知力好,27.6%的患者自知力受损.不同自知力患者在首次发作、病程、住院次数、临床症状、药物应用、氯丙嗪当量等临床方面,以及发病年龄、受教育时间人口学资料方面比较差异有统计学意义(P<0.05或0.01),但二者生活质量比较差异无统计学意义(P>0.05).回归分析显示,病程、阴性症状、不服药、苯二氮艹卓类药物使用率是自知力的独立影响因素(P<0.01).结论 社区精神分裂症患者自知力较好,自知力受病程、阴性症状等因素影响,与生活质量无关.
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