轻微精神病综合征患者症状学特征及共病精神障碍状况

摘要

目的：探讨轻微精神病综合征（APS）患者症状学特征及共病精神障碍状况。方法：使用精神病风险综合结构式访谈（SIPS）对101名精神科门诊求助者进行精神病风险症状评估，对其中符合APS 诊断标准者使用简明国际神经精神访谈（MINI）评估共病精神障碍情况。结果：检出28例（27.7％）求助者为 APS 患者，其中具有特异性风险症状“异常思维内容”或“猜疑被害观念”各21例（75％），非特异性风险症状“社交兴趣缺乏”12例（42.9％），一般症状“睡眠障碍”或“心境烦躁不安”各12例（42.9％）；19例（67.9％）共病≥1种精神障碍，其中11例（39.3％）为抑郁障碍，10例（35.7％）为焦虑障碍。结论：APS 患者常见的风险症状是思维障碍及社交兴趣缺乏；常共病抑郁障碍或焦虑障碍。%ObJective:To expore the symptoms characteristics and status of the comorbid psychiatric dis-order in patients with attenuated psychosis syndrome(APS). Method:The psychosis-risk symptoms were e-valuated using psychosis risk comprehensive structured interview(SIPS)in 101 psychological help-seeking peo-ple of psychiatric clinic;and status the comorbid psychiatric disorder for which conformed APS diagnosis stand-ard were assessed using mini-international neuropsychiatric interview(MINI). Results:Twenty-eight(27. 7% ) of the psychological help-seeking people were APS patients. The specific risk symptoms such as“ abnormal thinking content”and“suspicion murdered concept”were found each in 21 cases(75% );the non-specific risk symptoms such as“social interest lack”was found in 12 cases(42. 9% );the general symptoms such as“sleep disorder”and“mood irritability”were found each in 12 cases(42. 9% ). Nineteen cases(67. 9% )comorbid at the least one kind of psychiatric disorders,including 11 cases(39. 3% )comorbid depressive disorders,10 cases(35. 7% )comorbid anxiety disorder. Conclusion:The common psychosis-risk symptoms in APS pa-tients are thought disorder and lack of social interests;and often comorbid depression or anxiety disorders.