Objective To investigate the association between waist circumference and metabolic syndrome (MS) components rnin children and adolescents in Nanning. Methods Using a stratified random sampling method, 7 893 pupils of 6 to 18-yearold were selected from 14 schools out of a total of 396 primary and secondary schools in Nanning city. The selected pupils had undergone physical examination and blood biochemical test including fasting blood glucose (FBG), triglycerides (TG), and highdensity lipoprotein cholesterol (HDL-C). Results The abnormal indicators were detected in both boys and girls starting after 10-year-old in Nanning. It was consistent with IDF (2007) diagnostic criteria which stated that the diagnosis of MS is not made in children less than 10 years of age. The abnormal rates of MS components in rank order were HDL-C, TG, FBG and blood pressure in boys and girls, and abnormal rate of blood pressure and FBG in boys was higher than girls (P<0.05). In addition, the prevalence rate of MS increased with the increasing waist circumference. The rate of MS components was slightly increased when waist circumference was above the 75th percentile, while the rate was rernarkably increased when waist circumference was near the 90th percentile, but the mean of HDL-C showed the opposite direction. In comparison with children whose waist circumference was below the 75th percentile, the odds ratio of two MS risk factors doubled among children with waist circumference between 75th and 90th percentile and increased by 5 times in children with waist circumference above the 90th percentile. Except its negative correlation with HDL-C, the waist circumference was positively correlated with all other indicators. Conclusions Waist circumference and MS risk factors were closely related in children and adolescents. The mean (except HDL-C) and abnormal rate of MS risk factors increased with larger waist circumference.%目的 比较南宁地区不同腰围水平青少年罹患代谢综合征 (MS) 及各相关代谢指标异常率,探讨腰围与 MS危险因素的相关性.方法 采用分层整群随机抽样方法从南宁市396所中小学中抽取14所学校中6~18岁的中小学生 共 7 893名,进行体格检查及相关代谢生化数据的检测,包括空腹血糖 (FBG)、三酰甘油 (TG)、高密度脂蛋白胆固醇 (HDL-C).结果 南宁地区男女生均于10岁以后才逐渐出现各检测指标的异常,与IDF (2007) 诊断标准中<10岁不诊断 MS结果一致.MS相关指标异常率比较,男女生均依次为:HDL-C、TG、FBG、血压,且男生的血压和FBG异常率显 著高于女生,差异有统计学意义 (P <0.05).MS检出率随着腰围的增大而增加.腰围值P90者中该比例则增加400%.除 与HDL-C负相关外,腰围与其余指标呈正相关.结论 儿童青少年腰围与MS危险因素密切相关,各危险因素的均值 (除 HDL-C外) 及异常率随着腰围的增大而增加.
展开▼
