C反应蛋白联合降钙素原检测在老年社区获得性肺炎中应用126例临床观察

摘要

Objective To discuss the clinical application of Oreactive protein (CRP) combined with procalcitonin (PCT) detection in elderly patients with community-acquired pneumonia (CAP). Methods A total of 126 elderly CAP patients were randomly divided into bacterial group ( n = 66) , virus group ( n = 28) and mycoplasma group ( n =32) according to the results of laboratory tests. Another 47 healthy volunteers were included in the control group. The detections of CRP and PCT in different groups were compared. The relationship between the severity of pneumonia and CRP and PCT in the bacterial group was investigated. Results The CRP and PCT of four groups were statistically significant by means of variance analysis. In terms of CRP levels, the virus group showed no statistically significant difference when compared with the control group. The results of pairwise comparisons of the other groups were statistically significant. In terms of PCT levels, pairwise comparisons of the bacterial group and other groups were statistically significant. Compared with the control group, CRP and PCT levels in the bacterial group of different severity groups were statistically significant by means of variance analysis. Conclusion CRP combined with PCT has important clinical significance in detecting CAP pathogens, the judgment of the condition and the rational use of medicines.%目的 探讨C反应蛋白(CRP)、降钙素原(PCT)联合检测在老年社区获得性肺炎(CAP)诊断的临床应用价值.方法 选择本院老年CAP126例为研究对象,根据实验室检查分为细菌组66例、病毒组28例、支原体组32例,以47例健康体检人员为对照,比较各组别CRP、PCT检测情况,并研究细菌组中肺炎的严重程度与CRP、PCT的关系.结果 4组别CRP、PCT经方差分析均有统计学差异;CRP水平:病毒组与对照组比较无统计学差异,其他各组两两比较均有统计学差异;PCT水平:细菌组与其他各组两两比较均有统计学差异;细菌组不同严重程度分组中CRP、PCT水平与对照组比较,经方差分析均有统计学差异,各组别均有统计学差异.结论 CRP、PCT联合检测对CAP病原体的鉴别、病情的判断及合理用药有重要的临床意义.