首页> 中文期刊> 《实用临床医药杂志》 >75岁以上老年食管癌、贲门癌的外科治疗

75岁以上老年食管癌、贲门癌的外科治疗

         

摘要

Objective To summarize the clinical features and surgical treatment experience in patients over 75 years old with esophageal/gastric cardiac carcinoma. Methods The clinical data of 143 patients over 75 years old with esophageal/gastric cardiac carcinoma undergoing surgical treatment from Jan 2006 to Dec 2010 were retrospectively analyzed. There were 104 males and 39 females, aging from 75 to 91 years old, and 86 of the patients were complicated with various underlying diseases. All the patients underwent tumor resection via left thoracotomy, of whom 109 underwent left cervical esophagogastrostomy, 5 underwent supra-arch esophagogastrostomy, 24 underwent intra-arch esophagogastrostomy, and 5 underwent esophagojejunai anastomosis. Tubular gastroplasty was applied in the thoracic stomach construction. The patients received combined therapy in order to maintain heart and lung function and nutritional status. Results All patients went through the operation. Forty- three case- times of complications occurred, and all the patients recovered with conservative treatment except 1 case of respiratory failure. The patients were followed up for 1 to 5 years, and 6 were lost for follow - up. The 1 - year, 3 - year and 5 - year survival rate were 88. 3% , 54. 7% and 37. 8% , respectively. Conclusion Elderly patients with esophageal/ gastric cardiac carcinoma are commonly complicated with various basic diseases, which may affect the postoperative recovery. Careful surgical procedures and strengthened treatment may help most of the patients survive postoperatively.%目的 总结75岁以上高龄食管癌、贲门癌患者的临床特点及手术治疗经验.方法 回顾性分析本院2006年1月-2010年12月间接受手术治疗的140例75岁以上高龄食管癌、贲门癌患者的临床资料.结果 本研究无手术死亡病例.术后发生并发症43例,除1例呼吸衰竭难以纠正外,均经保守治疗后痊愈.随访1~5年,失访6例.术后1年生存率88.3%(121/137),3年生存率54.7% (47/86),5年生存率37.8%(14/37).死亡患者中与原发病相关者和非原发病相关者分别为49例和15例.结论 高龄食管癌、贲门癌患者体质较弱,常合并有其他多系统病症.细致的手术治疗和全面的围术期处理,可使大部分患者顺利度过围术期,取得满意疗效.

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