Objective To understand the common pathogens and resistant state of the inpa-tients in the geriatrics department and provide a reference for the clinical use of drugs. Methods A total of 300 inpatients in the geriatrics department from January 2010 to June 2012 were selected. Patients with infectious indicators were analyzed. Results A total of 169 patients took antimicrobial agents. Bacterial detection was used in all the non- surgical prevention antibacterials, and 176 pathogenic strains were found. The main infection sites were lower respiratory tract and urinary tract, and the major bacteria was G- bacteria. The detection rate of ESBLs producing escherichia coli was more than 75 % , oxacillin resistant staphylococcus epidermidis more than 80 % , and acine-tobacter baumannii of serious multiple - drug and pan - drug resistance. The second or third - generation cephalosporins and the third of quinolones (DDDs>70%) were the common clinically used drugs. Conclusion Inpatients in the geriatrics department in our hospital had serious bacterial resistance , In clinical practice, we should strengthen the surveillance of bacterial resistance and lighten the pressure of anti - infection treatment through timely treatment of original diseases, control of invasive treatment protocols, promoting reasonable application of antibiotics, and shortening of hospital stay.%目的 了解老年科住院患者常见病原菌及其耐药状况,为临床合理用药提供参考.方法 抽取2010年1月一2012年6月间老年科住院患者病例300份,对其中有感染指征的患者情况进行统计分析.结果 169例患者使用过抗菌药物,非手术预防用抗菌药物者均开展细菌检测,共检出176株病原菌.感染部位以下呼吸道和泌尿道感染为主,检出病原菌以G(-)居多.大肠埃希杆菌产ESBLs检出率＞75％,鲍曼不动杆菌多耐药和泛耐药严重,耐苯唑西林的表皮葡萄球菌＞80％.临床选择用药主要有第2、3代头孢霉素和第3代喹诺酮类等广谱抗生素(DDDs＞70％).结论 老年科住院患者细菌耐药状况严重,临床应加强细菌耐药检测工作,并通过及时治疗原发基础疾病、控制侵入性诊疗操作、促进合理使用抗菌药物、缩短住院时间等手段,以减轻抗感染治疗的压力.
展开▼
