口腔颌面部鳞状细胞癌患者不同原发灶部位与颈部Ⅰ、Ⅱ、Ⅲ、Ⅳ、Ⅴ区转移的相关性

摘要

目的 探讨口腔颌面部鳞状细胞癌患者不同原发灶部位与颈部Ⅰ、Ⅱ、Ⅲ、Ⅳ、Ⅴ区转移的相关性.方法 选取口腔颌面部鳞状细胞癌患者530例(561侧).所有患者行颈淋巴清扫术及原发灶切除术.记录清扫术方式及鳞状细胞癌的T分期,计算不同原发灶部位与颈部Ⅰ、Ⅱ、Ⅲ、Ⅳ、Ⅴ区的转移率.结果 有317侧颈部发生转移,总转移率为56.51%.Ⅰ、Ⅱ、Ⅲ、Ⅳ、Ⅴ区的转移率分别为20.67%、17.83%、9.80%、4.81%、3.39%.舌癌、舌根癌向II区转移的可能性较高,而口底癌、下牙龈癌、下颌骨中枢性颌骨癌、颊癌、上颌癌更偏向于Ⅰ区转移(P<0.05).磨牙后区癌Ⅰ、Ⅱ区转移率无显著差异(P>0.05).结论 口腔颌面部鳞状细胞癌向Ⅰ～Ⅲ区转移率较高.%Objective To explore the correlation between different primary site and Ⅰ,Ⅱ,Ⅲ,Ⅳ and Ⅴ districts transfeRin patients with squamous cell carcinoma of oral and maxillofacial region.Methods A total of 530 patients (561 sides) with squamous cell carcinoma of oral and maxillofacial region were selected and treated with radical neck dissection and primary resection.The surgical methods and T staging of squamous cell carcinoma were recorded,and different primary site and Ⅰ,Ⅱ,Ⅲ,Ⅳ and Ⅴ districts transfeRwere calculated.Results There were 317 sides of neck metastasis,and the total metastasis rate was 56.51%.TransfeRrates of Ⅰ,Ⅱ,Ⅲ,Ⅳ and Ⅴarea were 20.67%,17.83%,9.80%,4.81%,3.39% respectively.The possibility of tongue and root of tongue canceRmetastasis is high into the Ⅱ area,and the fooRof mouth,inferioRgingival,bucca,maxillary mandibulaRbone canceRtended to transfeRto Ⅰ area (P<0.05).There was no significant difference in Ⅰ and Ⅱ metastasis rate in carcinoma of the retromolaRtrigone (P>0.05).Conclusion The metastasis rate of oral squamous cell carcinoma is high in Ⅰ to Ⅲ area transfer.