血小板计数预测重度食管静脉曲张的临床意义

摘要

Objective To evaluate platelet count (PC) , a non - invasive index, in predicting the presence of large esophageal varices ( EV) in cirrhosis patients. Methods The analysis was performed in 80 patients with hepatic cirrhosis. PC were recorded in all the pa tients. The degree of esophageal varices in the patients were examined with electronic gastroscope. PC and electronic gastroscope were re checked after 1 month. Then the relationship between PC and degree of esophageal varices was evaluated. Results 5 patients withdrew be cause of upper gastrointestinal hemorrhage, and 3 patients did not recheck. PC in the large EV patients was obviously lower than that in non - large EV team ( P < 0.01). There was no significant difference in PC among the same degree of EV ( P > 0.05 ). PC decrease significantly in non - large EV patients whose EV aggravate into large degree ( P < 0.01). Conclusion PC is a non - invasive index to judge the large esophageal varices. The decrease of PC in short time may show that the degree of EV aggravate into large degree.%目的 探讨血小板计数(PC)在预测重度食管静脉曲张(EV)中的意义.方法 记录80例肝硬化患者的胃镜结果、PC1,1个月后复查胃镜及PC2.根据胃镜所见EV程度分为重度组和非重度组,对复诊前后PC变化及EV程度进行分析.结果 80例患者中5例因发生上消化道出血而退出观察、3例1个月后未复诊,72例完成该研究.重度组与非重度组PC差异有统计学意义(P＜0.01).1个月内EV程度无明显变化者PC差异亦无统计学意义(P＞0.05).1个月内由非重度EV发展为重度EV者复诊前后PC差异有统计学意义(P＜0.01).结论 PC可作为预测重度EV的指标,短期内PC明显下降可作为预测EV程度加重的指标.