PET/CT在肝细胞癌中的临床应用及进展

摘要

Hepatocellular carcinoma (HCC) has a high fatality rate and most patients are in advanced stage when diagnosed with routine methods.As a molecular imaging method, positron emission tomography/computed tomography (PET/CT) has become more and more important.However, it also has certain limitations, since it always has false-negative results for well-differentiated HCC and small HCC.Therefore, a combination of various tracers can improve the sensitivity and specificity of PET/CT in the diagnosis of HCC.This article reviews the role of PET/CT in the therapeutic effect evaluation, recurrence monitoring, and prognosis of HCC.%肝细胞癌病死率很高,常规诊断发现时患者多为中晚期.PET/CT作为分子影像的方法之一,已显现出越来越重要的作用.然而,其也具有一定的局限性,如对高分化肝细胞癌及小肝癌的诊断多为假阴性.因此联合应用多种示踪剂可以提高PET/CT显像对肝细胞癌诊断的灵敏度和特异度.对PET/CT在肝细胞癌的疗效评估、复发监测及预后方面的研究进展进行了介绍.