胰腺癌根治术淋巴结清扫范围的发展历程

摘要

胰腺癌是所有消化系统恶性肿瘤中患者预后情况最差的之一，总体5年生存率仅约5％，即使进行了根治性切除，患者5年生存率也仅为20％左右。复发和转移是影响胰腺癌患者术后生存的最关键因素，其中易发生淋巴结转移是胰腺癌的重要特点，因而淋巴结的清扫范围一直是胰腺癌根治术的一个热点问题。对胰腺癌根治术淋巴结清扫范围的历史与现状进行了总结，认为规范化的淋巴结清扫是改善胰腺癌术后患者预后的关键因素之一。%Pancreatic cancer is one of the digestive malignant tumors with the worst prognosis and has an overall 5 -year survival rate as low as 5%.Even though radical resection is performed,the 5 -year survival rate is only about 20%.Recurrence and metastasis are the most important influencing factors for the postoperative survival of patients with pancreatic cancer.Lymph node metastasis is an important feature of pancreatic cancer,and the extent of lymph node dissection has always been a hot topic in radical surgery for pancreatic cancer.This arti-cle summarizes the history and current status of the extent of lymph node dissection in pancreatic cancer and points out that standardized lymph node dissection is a key factor for improving patients′prognosis after pancreatic cancer surgery.