急诊经皮冠脉介入术与溶栓对急性心肌梗死的疗效对比

摘要

Objective Comparison of emergency percutaneous coronary intervention clinical efficacy of thrombolysis in patients with acute myocardial infarction. Methods Forty-seven patients with acute myocardial infarction were randomly divided into study group and control group, each group of 37 patients,study group used emergency percutaneous coronary intervention,the control group used thrombolytic therapy,and com-pared the changes of ST segment (EST)and serum troponin levels in ECG at two different time intervals. Results After the operation of ST epsi-lon two groups changes were compared with the preoperative postoperative decline,research group 72 h ST 0. 03 ± 0. 02 cm epsilon recovery effect was significantly better than the control group 0. 21 ± 0. 11 cm,there was significant difference was statistically significant (P < 0. 05). Two groups of postoperative troponin 8 h largest increase,and the study group was 34. 61 ± 4. 76 U/ L,the control group is 27. 34 ± 4. 56 U/ L;24 h and 72 h decreased the results for the 8. 87 ± 2. 21 U/ L,0. 21 ± 0. 08 U/ L was significantly lower than the control group 9. 36 ± 3. 47 U/ L,4. 61 ± 1. 13 U/ L in the study,there are significant differences,with statistical significance (P < 0. 05). Conclusion The clinical curative effect of treatment is better than thrombolysis in patients with acute myocardial infarction patients by emergency percutaneous coronary intervention,cardiac systolic function in patients with improvement of better effect,can improve the clinical treatment effect,shorten recovery time,reduce the recur-rence of symptoms and mortality and improve the prognosis of patients,worthy of promotion.%目的 对比急诊经皮冠脉介入术与溶栓对急性心肌梗死的临床疗效.方法 将收治的74例急性心肌梗死患者随机分为研究组和对照组实行对比观察,每组37例.研究组使用急诊经皮冠脉介入术,对照组使用溶栓治疗,对比两组不同时段的心电图ST段(EST)变化和血清肌钙蛋白水平.结果 术后两组的EST变化均较术前有所回落,术后72 h研究组的EST恢复效果(0.03±0.02 cm)明显优于对照组(0.21±0.11 cm),差异有显著性(P<0.05);两组术后8 h肌钙蛋白上升幅度最大,且研究组(34.61±4.76 U/L)高于对照组(27.34±4.56 U/L);24 h、72 h下降研究组结果为8.87±2.21 U/L、0.21±0.08 U/L,明显低于对照组9.36±3.47 U/L、4.61±1.13 U/L,差异有显著性(P<0.05).结论 急诊经皮冠脉介入术治疗急性心肌梗死患者所获得的临床疗效优于溶栓,患者的心肌收缩功能改善效果更佳,值得临床推广应用.