Objective To explore the difference of local microcirculation and inflammatory condition in patients with uterine fibroids with laparoscopic hysteromyoma removal and traditional open abdominal hysteromyoma. Methods 90 cases of uterine fibroids were selected from May 2013 to June 2015,and were randomly divided into observation group and control group,45 cases in each group. Laparoscopic hysteromyoma re-moval was performed in the observation group,and the control group was treated with an open abdominal myoma. To observe and record the chan-ges of 1 d,3 d,7 d microcirculation index and inflammatory cytokines before and after operation. Results The CRP,IL - 6 and tnf - alpha in the serum of the two groups preoperative had no significant difference (P > 0. 05). The contents of CRP,IL - 6 and tnf - alpha in the 1 d,3 d and 7 d observation groups were significantly lower than those in the control group (P 0.05);而术后1 d、3 d、7 d观察组的CRP、IL-6、TNF-α 含量显著少于对照组(P0.05),术后1 d、3 d、7 d观察组血流灌注、红细胞聚集指数异常率、甲襞微循环中的管襻形态积分和血液流态积分值显著低于对照组(P<0.05);且术后1 d、3 d、7 d观察组毛细血管管径、宫颈血管清晰率显著高于对照组(P<0.05).结论 腹腔镜下子宫肌瘤剔除术对机体的应激、创伤更小,微循环功能更好,有利于患者术后的恢复,值得在临床上推广应用.
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