脾肾俞穴位埋线对原发性骨质疏松妇女内分泌激素的调控作用

摘要

Objective :Through observing the change in the level of serum estradiol (E2), testosterone (T) and parathyroid hormone ( PTH), to investigate clinical efficacy of catgut - embedding therapy in pishu and shenshu on the change of endocrine hormone of women with primary osteoporosis.Methods:Sixty women patients with primary osteoporosis were randomly assigned into acupoint catgut - embedding ( n = 30 ) group and acupuncture group ( n = 30) ,6 weeks after treatment, patients were evaluated with the level of serum estradiol ( E2 ), testosterone (T) and parathyroid hormone ( PTH ).Results: ①E2, T: Compared with baseline data, serum estradiol ( E2 ) and testosterone (T) of both groups after treatment are increased and significant differences were showed in both groups ( P ＜ 0.05 ).There were not significant differences between the two groups ( P ＞0.05);②PTH :Compared with the data before the treatment,both groups were not significant differences after the treatment ( P ＞ 0.05 ).There were not significant differences between acupoint catgut - embedding group and acupuncture group(P ＞ 0.05 ).Conclusion:Both acupuncture and acupoint catgut- embedding therapy in pishu and shenshu can make the level of serum estradiol ( E2 ) and testosterone (T) of women with primary osteoporosis rise after 6 weeks treatment.The level of parathyroid hormone (PTH) is not strongly influenced by the two types treatments.The mechanism of clinical efficacy of acupuncture and acupoint catgut- embedding methed in pishu and shenshu for primary osteoporosis depends on increasing the level of serum estradiol ( E2 ) and testosterone (T).%目的:通过观察血清雌二醇(E2).睾酮(T)以及甲状旁腺激素(PTH)的变化,探讨脾肾俞穴位埋线对原发性骨质疏松妇女内分泌激素的调控作用.方法:选择原发性骨质疏松妇女60名,随机分为埋线组和针刺组各30例,连续治疗6周,分别于治疗前及治疗后检测血清E2,T和PTH.结果:①E2,T:两组治疗后血清E2,T均升高,较治疗前差异均有显著性(P<0.05),两组间比较差异无显著性(P>0.05);②PTH:两组治疗后血清PTH均无明显变化,较治疗前差异均无显著性(P>0.05),两组间比较,差异无显著性(P>0.05).结论:脾俞、肾俞穴位埋线或针刺治疗6周都能使原发性骨质疏松妇女血清E2,T升高,对PTH的影响不明显,表明提高血清E2,T是脾俞、肾俞穴位埋线或针刺治疗原发性骨质疏松症的内分泌作用机制.