颈动脉粥样硬化与不同类型冠心病的相关性分析

摘要

Objective To determine the relationship between the aggravation of CAAS and coronary atherosclerosis (CAS) ;and to summarize the pathologic character of CAAS of the patients with various coronary artery disease. Methods Review the result of coronary angiography and carotid artery ultrasonography and the related risk factors of the patients who were diagnosed as CAD through coronary angiography ( CAG). The patients were divided into the scleratheroma group and the non scleratheroma group. The patients were divided into stable angina pectoris( AP) group, unstable angina pectoris(UAP) group and acute myocardial infarction (AMI) group according to the criterion of coronary artery disease of WHO. The patients were divided into group A (coronary artery of single vessel lession) ,group B( coronary artery of double vessel lession ) , group C( coronary artery of triple vessel lession )and group D(left main vessel lession ).The aggravation of CAAS was graded. Results There were 198 patients with various CAAS among 228 patients with coronary artery disease ( 86. 8%). CAAS was much related with hypertension and non-related with age, sex, BMI, smoking, drinking, hyperlipoidemia, hyperuricosuria and diabetes mellitus. The aggravation of CAAS much graver with much graver CAS. But only the plaque number of Group A was more than Group D( P ＜0. 05). The grading integral and Crouse integral of CAAS of AP group was not remarkable less than UAP group. The grading integral of CAAS of AP group was less than AMI group and the Crouse integral of AP group was more. But there was no remarkable difference. The number of all plaque,plaque and plaque of AP group was not remarkable less than UAP group and AMI group. There was the plaque among the three group. Conclusion Carotid artery atherosclerosis (CAAS) is relative to coronary artery disease ( CAD).%目的 探讨冠心病病人颈动脉粥样硬化程度与冠状动脉粥样硬化(CAAS)程度的关系及相关危险因素;总结不同类型冠心病患者颈动脉粥样硬化(CAS)病理特点.方法 回顾性分析228例经冠状动脉动脉造影确诊为冠心病的病例冠状动脉造影结果、颈动脉超声检测结果及相关危险因素;根据颈动脉是否有粥样硬化分为粥样硬化组及非粥样硬化组;根据WHO诊断标准将病例分为稳定型心绞痛组、不稳定型心绞痛组及心肌梗死组;根据冠状动脉造影结果将病例分为单支病变组(组A)、双支病变组(组B)、三支病变组(组C)及左主干组(组D);对颈动脉粥样硬化(CAS)程度进行积分处理.结果 发现228例冠心病病人中198例均有不同程度颈动脉粥样硬化,发病率86.8%;颈动脉粥样硬化(CAS)与高血压显著相关,与年龄、性别、体重指数、吸烟、嗜酒、高脂血症、高尿酸血症及糖尿病无明显相关;颈动脉粥样硬化(CAS)程度随冠状动脉粥样硬化(CAAS)的程度加重而加重,但仅仅一支病变组总斑块数显著低于左主干组(P＜0.05);稳定型心绞痛组的颈动脉等级积分、Crouse积分均低于不稳定型心绞痛组;稳定型心绞痛组颈动脉等级积分(grading integral)较急性心肌梗死组低,而Crouse积分高于急性心肌梗死组;稳定型心绞痛组的总斑块数、扁平斑数及软斑数均低于不稳定型心绞痛组及急性心肌梗死组,三组的硬斑数差异无统计学意义(P＞0.05).三组均未发现溃疡斑.结论 颈动脉粥样硬化与冠心病有相关性.